Novel chemical starting points
ULTIMATE introduces completely novel heterocycles and building blocks. Novelty is assured at atom graph and scaffold levels against public domain chemistry and patent databases.
Excellent druglike sets
ULTIMATE development is guided by pharma industry experts and thus it is systematically filtered by physicochemical properties (e.g. Fsp3, logP) and against unwanted substructures.
Mcule's chemistry experts generate focused, diverse FRAGMENT, DNA-ENCODED, PHENOTYPIC, CNS, PPI etc. ULTIMATE libraries custom-tailored for your project needs.
High success rate
Mcule's artificial chemist algorithm (ARCHIE) ensures over 80% average synthetic feasibility rate by encoding robust, well-validated reactions rigorously reviewed by chemistry experts.
Delivery on time
ULTIMATE is based on readily available in-stock building blocks and the chemistry expertise of well-established supplier partners to enable delivery in 2-6 weeks.
ULTIMATE has pre-calculated prices to ensure fixed costs and competitive budget vs. FTE-based custom synthesis. Discounts based on amounts and order size.